Researchers from the UNC School of Medicine create the first ever mouse model of ovarian clear cell carcinoma using data gleaned from the human cancer genome atlas. They show how when the genes ARID1A and PIK2CA are mutated in specific ways, the result is the most severe form of ovarian cancer 100 percent of the time. In their paper in Nature Communications, they also show that a known drug can suppress tumor growth.
Among the research institutions NCI funds across the United States, it currently designates 68 as Cancer Centers. Largely based in research universities, these facilities are home to many of the NCI-supported scientists who conduct a wide range of intense, laboratory research into cancer’s origins and development. The Cancer Centers Program also focuses on trans-disciplinary research, including population science and clinical research. The centers’ research results are often at the forefront of studies in the cancer field.