Baylor study finds ovarian cancer arises in fallopian tube of knockout mice
The most deadly form of “ovarian” cancer arises in the fallopian tubes – not the ovaries – of knockout mice that lack two genes associated with the disease, said researchers led by Baylor College of Medicine in a report that appears online in the journal Proceedings of the National Academy of Sciences. In this study, scientists show that the disease that is typically called “ovarian” cancer does not arise within the ovary but instead from the fallopian tubes in mice that lack two genes – Dicer and Pten. Mutations in each gene have recently been shown to be altered in women with high-grade serious ovarian cancer.
Among the research institutions NCI funds across the United States, it currently designates 66 as Cancer Centers. Largely based in research universities, these facilities are home to many of the NCI-supported scientists who conduct a wide range of intense, laboratory research into cancer’s origins and development. The Cancer Centers Program also focuses on trans-disciplinary research, including population science and clinical research. The centers’ research results are often at the forefront of studies in the cancer field.